Description

8'-Chloro-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline] is a sophisticated spirocyclic organic compound that serves as a critical building block in advanced chemical synthesis. Its unique molecular architecture, featuring a fused cyclopropane and isoquinoline system, makes it a valuable intermediate for pharmaceutical research and development. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and exploring new chemical spaces.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly for central nervous system (CNS) and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its spirocyclic structure for bioactive molecule design.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study biological pathways and protein interactions.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials with specific electronic or structural properties.
• Catalyst Ligand Development: Potential use in the synthesis of novel chiral ligands for asymmetric catalysis.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Item	Details
Product Name	8'-Chloro-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline]
CAS No.	885269-35-2
Molecular Formula	C12H12ClN
Molecular Weight	205.68 g/mol
Synonyms	8'-Chloro-1'H-spiro[cyclopropane-1,4'-isoquinoline]-2',3'-dihydro; 1'H-Spiro[cyclopropane-1,4'-isoquinoline], 8'-chloro-2',3'-dihydro-; 885269-35-2; Spiro[cyclopropane-1,4'-isoquinoline], 8'-chloro-2',3'-dihydro-1'H-; 8-Chloro-2,3-dihydro-1H-spiro[cyclopropane-1,4-isoquinoline]; 8'-Chloro-2',3'-dihydrospiro[cyclopropane-1,1'-isoquinoline]
EINECS	Contact for details

Quality Control

Our 8'-Chloro-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline] is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.