Description

6'-Bromo-2',3'-Dihydro-1'H-Spiro[Cyclopropane-1,4'-Isoquinoline is a high-value, spirocyclic organic building block of significant interest in advanced pharmaceutical research and development. Its unique molecular architecture, featuring a fused isoquinoline core with a cyclopropane ring, makes it a critical intermediate for constructing complex bioactive molecules. This compound is primarily sought after by medicinal chemists and R&D teams in the pharmaceutical and agrochemical industries for the synthesis of novel drug candidates and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential therapeutic agents, particularly for central nervous system (CNS) targets and other biologically active compounds.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities and develop novel pharmacophores.
• Agrochemical Development: Serves as a precursor in the research and synthesis of new crop protection agents and pesticides.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target validation.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for fundamental organic synthesis and methodological studies.
• Fine Chemical Synthesis: Acts as a specialized intermediate for the production of other complex, high-value spirocyclic and heterocyclic compounds.

Basic Information

Product Name	6'-Bromo-2',3'-Dihydro-1'H-Spiro[Cyclopropane-1,4'-Isoquinoline
CAS No.	885269-25-0
Molecular Formula	C11H10BrN
Molecular Weight	236.11 g/mol
Synonyms	6'-Bromo-1'H-spiro[cyclopropane-1,4'-isoquinoline]; 6'-Bromo-2',3'-dihydrospiro[cyclopropane-1,4'-isoquinoline]; 6'-Bromo-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline]; 1'H-Spiro[cyclopropane-1,4'-isoquinoline], 6'-bromo-2',3'-dihydro-; 6-Bromo-2,3-dihydro-1H-spiro[cyclopropane-1,4'-isoquinoline]; 6'-Bromo-1'H-spiro[cyclopropane-1,4'-isoquinoline]-2',3'-dihydro; 885269-25-0
EINECS	Contact for details

Quality Control

Our 6'-Bromo-2',3'-Dihydro-1'H-Spiro[Cyclopropane-1,4'-Isoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our commitment to quality ensures the material meets the high standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.