Description

tert-Butyl 2,7-diazaspiro[4.5]decane-2-carboxylate is a high-value, nitrogen-containing spirocyclic building block widely used in modern pharmaceutical discovery and development. Its rigid, three-dimensional structure is crucial for creating novel molecular scaffolds with enhanced biological activity and improved drug-like properties. This compound is primarily utilized by medicinal chemists and research organizations in the pharmaceutical and agrochemical industries for the synthesis of new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of drug candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Medicinal Chemistry Scaffold: Used to explore structure-activity relationships (SAR) due to its spirocyclic architecture, which can improve potency and selectivity.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a linker or core component in the design of bifunctional molecules for targeted protein degradation.
• Agrochemical Research: Employed in the discovery of new herbicides, fungicides, and insecticides with novel modes of action.
• Chemical Biology Probes: Utilized to create tool compounds for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for custom synthesis projects and library production.

Basic Information

Product Name	tert-Butyl 2,7-diazaspiro[4.5]decane-2-carboxylate
CAS No.	885268-42-8
Molecular Formula	C13H24N2O2
Molecular Weight	240.34 g/mol
Synonyms	2,7-Diazaspiro[4.5]decane-2-carboxylic acid, 1,1-dimethylethyl ester; tert-Butyl 2,7-diazaspiro[4.5]decane-2-carboxylate; 2-tert-Butoxycarbonyl-2,7-diazaspiro[4.5]decane; Boc-2,7-diazaspiro[4.5]decane; 2-(tert-Butoxycarbonyl)-2,7-diazaspiro[4.5]decane; 2,7-Diazaspiro[4.5]decane-2-carboxylic acid tert-butyl ester; 1,1-Dimethylethyl 2,7-diazaspiro[4.5]decane-2-carboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl 2,7-diazaspiro[4.5]decane-2-carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. Certificates of Analysis (COA) with detailed specifications are provided for each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.