Description

1-(5-Bromo-3-Methylpyridin-2-Yl)-4-Methylpiperazine is a high-purity, advanced pharmaceutical intermediate with the CAS number 885267-44-7. This compound is valued for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is essential for R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries seeking reliable, high-quality intermediates for innovative drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially for neurological and oncological targets.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a core scaffold for constructing complex molecules in the final stages of API manufacturing.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization within drug discovery pipelines.
• Contract Research & Manufacturing (CRO/CMO): Supplied to outsourcing partners for custom synthesis and scale-up projects under GMP or non-GMP conditions.
• Bioconjugation & Probe Development: Potential utility in creating chemical probes or labeled compounds for biochemical and diagnostic applications.
• Academic Research: Employed in university and institutional labs for fundamental organic synthesis and pharmacological studies.

Basic Information

Product Name	1-(5-Bromo-3-Methylpyridin-2-Yl)-4-Methylpiperazine
CAS No.	885267-44-7
Molecular Formula	C11H16BrN3
Molecular Weight	270.17 g/mol
Synonyms	4-Methyl-1-(5-bromo-3-methyl-2-pyridinyl)piperazine; 1-(5-Bromo-3-methylpyridin-2-yl)-4-methylpiperazine; 5-Bromo-3-methyl-2-(4-methylpiperazin-1-yl)pyridine; 2-(4-Methylpiperazin-1-yl)-5-bromo-3-methylpyridine; 885267-44-7; 5-Bromo-3-methyl-2-(4-methyl-1-piperazinyl)pyridine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized and controlled using advanced analytical techniques, including HPLC, GC, NMR, and mass spectrometry. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality management system supports the needs of research and cGMP manufacturing, ensuring traceability, consistency, and reliability for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere if necessary to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.