Description

2-Bromo-5-Chloro-4-Methylpyridine is a high-purity halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and R&D professionals developing new active ingredients, where its specific substitution pattern enables precise molecular modifications.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogenated structure.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and liquid crystals.
• Chemical Biology: Employed as a probe or labeling reagent in biochemical studies and diagnostic assay development.
• Cross-Coupling Reactions: A valuable substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.
• Academic & Industrial R&D: Fundamental research chemical for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	2-Bromo-5-Chloro-4-Methylpyridine
CAS No.	885267-40-3
Molecular Formula	C6H5BrClN
Molecular Weight	206.47 g/mol
Synonyms	5-Chloro-2-bromo-4-methylpyridine; 4-Methyl-2-bromo-5-chloropyridine; 2-Bromo-5-chloro-4-picoline; 885267-40-3; Pyridine, 2-bromo-5-chloro-4-methyl-
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Chloro-4-Methylpyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.