Description

2-Bromo-5-(Cyclobutanoylamino)-Pyridine is a high-purity, advanced pharmaceutical intermediate characterized by its bromopyridine core functionalized with a cyclobutanoylamino group. This compound matters for its critical role as a versatile building block in modern medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its heterocyclic structure for bioactivity.
• Chemical Biology: Serves as a probe or linker in the development of chemical tools for studying biological pathways.
• Material Science: Potential precursor for the synthesis of specialized ligands and functionalized polymers.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services.

Basic Information

Product Name	2-Bromo-5-(Cyclobutanoylamino)-Pyridine
CAS No.	885267-03-8
Molecular Formula	C10H11BrN2O
Molecular Weight	255.11 g/mol
Synonyms	2-Bromo-5-(cyclobutanecarboxamido)pyridine; 5-Amino-2-bromopyridine cyclobutanoyl derivative; N-(6-Bromopyridin-3-yl)cyclobutanecarboxamide; 2-Bromo-5-cyclobutanamidopyridine; Cyclobutanecarboxylic acid (6-bromo-3-pyridinyl)amide; BR-885267-03-8; 885267-03-8
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-(Cyclobutanoylamino)-Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.