Description

Methyl 4-[(9H-Fluoren-9-Ylmethoxycarbonylamino)Methyl]Benzoate is a specialized Fmoc-protected amino acid derivative, a critical building block in solid-phase peptide synthesis (SPPS). Its value lies in enabling the precise and efficient construction of complex peptides by protecting the reactive amine group during chain elongation. This high-purity intermediate is essential for researchers and manufacturers in pharmaceutical development, biotechnology, and advanced materials science who require reliable, high-quality reagents for producing therapeutic peptides and peptidomimetics.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid derivative for the automated, sequential assembly of peptide chains.
• Pharmaceutical Research & Development: Used in the synthesis of novel peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Bioconjugation: Serves as a linker or spacer molecule for attaching peptides to other biomolecules, surfaces, or polymers.
• Combinatorial Chemistry: A valuable building block for creating diverse libraries of peptide compounds for screening.
• Proteomics and Biochemical Research: Employed in the study of protein-protein interactions and the synthesis of labeled or modified peptide probes.
• Custom Peptide Service Providers: A fundamental raw material for CROs and CDMOs offering bespoke peptide manufacturing.

Basic Information

Product Name	Methyl 4-[(9H-Fluoren-9-Ylmethoxycarbonylamino)Methyl]Benzoate
CAS No.	885266-54-6
Molecular Formula	C24H21NO4
Molecular Weight	387.43 g/mol
Synonyms	Fmoc-4-Aminomethylbenzoic Acid Methyl Ester; Methyl 4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)benzoate; 4-(Fmoc-Aminomethyl)benzoic Acid Methyl Ester; Fmoc-AMB-OMe; Fmoc-protected AMB Methyl Ester; (4-(Fmoc-aminomethyl)phenyl)carboxylic Acid Methyl Ester; Methyl p-((Fmoc-amino)methyl)benzoate; 4-[(Fmoc-amino)methyl]benzoic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our Methyl 4-[(9H-Fluoren-9-Ylmethoxycarbonylamino)Methyl]Benzoate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, typically ≥98% (HPLC). Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with cGMP guidelines for advanced intermediates and can provide material suitable for research and development under stringent quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.