Description

1-(2-Chloro-5-Methylpyridin-3-Yl)Ethanone is a high-purity pyridine derivative building block essential for advanced organic synthesis. This compound matters as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its specific substitution pattern enables targeted molecular construction. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with specific biological activities.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research.
• Agrochemical Synthesis: Used in the development and production of advanced pesticides, herbicides, and fungicides, leveraging its heterocyclic structure.
• Chemical Research & Development: Serves as a versatile precursor in organic synthesis for creating complex molecules in academic and industrial R&D settings.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands and organocatalysts used in asymmetric synthesis and metal-catalyzed reactions.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and functional polymers due to its aromatic pyridine core.

Basic Information

Product Name	1-(2-Chloro-5-Methylpyridin-3-Yl)Ethanone
CAS No.	885223-64-3
Molecular Formula	C8H8ClNO
Molecular Weight	169.61 g/mol
Synonyms	3-Acetyl-2-chloro-5-methylpyridine; 2-Chloro-5-methyl-3-acetylpyridine; 1-(2-Chloro-5-methyl-3-pyridinyl)ethanone; Ethanone, 1-(2-chloro-5-methyl-3-pyridinyl)-; 2-Chloro-5-methylpyridin-3-yl methyl ketone
EINECS	Contact for details

Quality Control

Our 1-(2-Chloro-5-Methylpyridin-3-Yl)Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.