Description

Methyl 2-(5-Bromo-2-Fluorophenyl)Acetate is a high-purity fluorinated and brominated aromatic ester, serving as a critical advanced intermediate in modern organic synthesis. This compound is valued for its unique halogenated phenylacetic acid ester structure, which provides versatile reactivity for constructing complex molecular architectures. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, leveraging the fluorine and bromine substituents for enhanced bioactivity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated organic compounds used in electronic displays and optoelectronic devices.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to form biaryl structures.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries for screening.
• Fine Chemical Production: Utilized in the custom synthesis of specialty chemicals, dyes, and complex fragrance molecules.

Basic Information

Product Name	Methyl 2-(5-Bromo-2-Fluorophenyl)Acetate
CAS No.	885068-47-3
Molecular Formula	C9H8BrFO2
Molecular Weight	247.06 g/mol
Synonyms	Methyl (5-Bromo-2-fluorophenyl)acetate; (5-Bromo-2-fluorophenyl)acetic acid methyl ester; Methyl 5-bromo-2-fluorobenzeneacetate; 2-(5-Bromo-2-fluorophenyl)acetic acid methyl ester; Methyl α-(5-bromo-2-fluorophenyl)acetate; 885068-47-3; Methyl 2-(5-Bromo-2-fluoro-phenyl)acetate
EINECS	Contact for details

Quality Control

Our Methyl 2-(5-Bromo-2-Fluorophenyl)Acetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.