Description

Panobacumab is a human monoclonal antibody specifically developed for therapeutic intervention against severe bacterial infections. This product is critical for addressing the growing global challenge of antibiotic-resistant pathogens, offering a targeted immunological approach. It is primarily utilized by pharmaceutical manufacturers, biotechnology research institutions, and clinical development organizations engaged in advanced infectious disease therapeutics.

Application

• Therapeutic Development: Primary active pharmaceutical ingredient (API) for novel anti-infective biologics targeting Pseudomonas aeruginosa.
• Clinical Research: Critical reagent in preclinical and clinical studies investigating immunotherapeutic strategies for hospital-acquired infections.
• Biodefense: Potential component in strategic stockpiles for treating infections caused by multidrug-resistant (MDR) bacterial agents.
• Combinatorial Therapy: Used in research to evaluate synergistic effects with conventional antibiotics to enhance efficacy and overcome resistance.
• Diagnostic Tool Development: Serves as a reference standard in the development of immunoassays for pathogen detection and serotyping.

Basic Information

Product Name	Panobacumab
CAS No.	885053-97-4
Molecular Formula	Data on file
Molecular Weight	Approx. 150 kDa (Contact for details)
Synonyms	Anti-Pseudomonas aeruginosa Human Monoclonal Antibody; KBPA-101; Aerumab; Monoclonal Antibody KBPA101; Anti-LPS O11 Human IgG1κ; Human Anti-P. aeruginosa O11 IgG1 Monoclonal Antibody; Panobacumab (INN); UNII-6QZ1HYV6A8
EINECS	Contact for details

Quality Control

Our Panobacumab is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, potency, and safety, meeting the stringent requirements for biopharmaceutical development. Certificates of Analysis (COA) detailing specifications such as purity (by SEC-HPLC), endotoxin levels, sterility, and binding activity are provided.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure containers are sealed under controlled, dry conditions.

Specification

Item	Specification
Appearance	Clear to slightly opalescent, colorless to pale yellow solution
Identification (HPLC/ELISA)	Conforms to reference standard
Purity (SEC-HPLC)	≥ 95.0% (Monomer)
Protein Concentration	As per COA (typically 1-10 mg/mL)
Potency (Binding Assay)	≥ 90% relative activity
Endotoxin	< 1.0 EU/mg
Sterility	Sterile (or meets applicable pharmacopeial limits)
pH	6.0 - 7.5

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.