Description

Rovelizumab [Usan:Inn] CAS NO 197099-66-4 is a humanized monoclonal antibody developed for therapeutic applications. This compound is significant for its targeted mechanism of action, offering high specificity and potency in clinical settings. It is primarily required by the pharmaceutical and biotechnology industries for research and development into novel immunotherapies and treatment modalities.

Application

• Primary research and development of novel immunomodulatory therapies.
• Pre-clinical and clinical studies investigating inflammatory and autoimmune disease pathways.
• Use as a critical reference standard in bioanalytical method development and validation.
• Component in the formulation of investigational new drugs (INDs) for regulatory submissions.
• Tool compound for studying specific cell surface receptor interactions and signaling cascades.
• Potential use in the development of companion diagnostics for targeted therapies.

Basic Information

Product Name	Rovelizumab [Usan:Inn]
CAS No.	197099-66-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Rovelizumab; Anti-LFA-1 Antibody; LeukArrest; hu1124; Immunoglobulin G1, anti-(human antigen CD11a (integrin α-L)) (human-mouse monoclonal hu1124 gamma1-chain), disulfide with human-mouse monoclonal hu1124 κ-chain, dimer; INN: Rovelizumab; USAN: Rovelizumab
EINECS	Contact for details

Quality Control

Our Rovelizumab is produced and handled under stringent quality systems. Each batch undergoes comprehensive analytical testing, including but not limited to assays for purity, potency, identity, and sterility, ensuring it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store frozen at -20°C or below. Avoid repeated freeze-thaw cycles. This product is hygroscopic (moisture-sensitive) and should be handled under controlled, dry conditions to maintain integrity.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or clear solution
Identification (HPLC/MS)	Conforms to reference standard
Purity (SDS-PAGE / SEC-HPLC)	> 95%
Protein Content (UV)	As per COA
Biological Activity (Cell-based assay)	As per COA
Endotoxin (LAL)	< 1.0 EU/mg
Sterility (Membrane Filtration)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.