Description

Tuvirumab CAS NO 138660-97-6 is a monoclonal antibody (mAb) therapeutic agent, representing a critical tool in targeted immunotherapy. Its primary value lies in its specific binding affinity, which enables precise intervention in disease pathways. This product is essential for research and development in the biopharmaceutical sector, particularly for organizations focused on oncology and immunology.

Application

• Biopharmaceutical Research & Development: A key reference standard for the development and validation of novel therapeutic antibodies and biosimilars.
• Preclinical & Clinical Studies: Used in in vitro and in vivo studies to investigate mechanisms of action, pharmacokinetics, and efficacy.
• Diagnostic Assay Development: Serves as a critical component in the creation of immunoassays, ELISA kits, and other diagnostic tools for biomarker detection.
• Cell Biology & Immunology Research: Employed to study specific cell surface receptors, signal transduction pathways, and immune cell functions.
• Quality Control & Validation: Acts as a positive control or comparator in the quality assurance testing of related biopharmaceutical products.

Basic Information

Product Name	Tuvirumab
CAS No.	138660-97-6
Molecular Formula	Contact for details
Molecular Weight	Approx. 150 kDa (Monoclonal IgG)
Synonyms	Anti-CD147 monoclonal antibody; Tuvirumab (INN); CD147 mAb; Basigin monoclonal antibody; EMMPRIN antibody; 5A12; TUV; Monoclonal antibody to CD147
EINECS	Not listed / Contact for details

Quality Control

Our biopharmaceutical products are manufactured and tested under stringent quality systems. Each batch of Tuvirumab is subjected to a comprehensive panel of analytical tests to ensure identity, purity, potency, and safety, adhering to relevant ICH guidelines. A detailed Certificate of Analysis (COA), including data on purity (by SEC-HPLC and CE-SDS), endotoxin levels, sterility, and binding activity, is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Avoid repeated freeze-thaw cycles. Upon receipt, aliquot as needed and store under recommended conditions. The product is hygroscopic (moisture-sensitive).

Specification

Item	Specification
Appearance	Clear to slightly opalescent, colorless to pale yellow solution
Identification (SEC-HPLC / CE-SDS)	Conforms to reference standard
Purity (Monomer by SEC-HPLC)	≥ 95.0%
Protein Concentration (A280)	1.0 ± 0.2 mg/mL (or as specified)
Potency (Binding ELISA / SPR)	≥ 90% relative activity
Endotoxin	< 1.0 EU/mg
Sterility (Membrane Filtration)	Sterile
Buffer	PBS, pH 7.2 - 7.6

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.