Description

2-Bromo-3-(Methylthio)Pyridine is a high-purity, versatile heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic placement of bromine and methylthio substituents on the pyridine ring, enabling precise functionalization for creating complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it serves as a key intermediate in the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, and fungicides, leveraging its reactive sites for structural diversification.
• Ligand & Catalyst Development: Serves as a starting material for constructing specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of functionalized pyridine derivatives for advanced materials, such as organic semiconductors and liquid crystals.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) to form new carbon-carbon bonds.
• Custom Synthesis & Contract Manufacturing: A valuable building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Bromo-3-(Methylthio)Pyridine
CAS No.	884863-17-6
Molecular Formula	C7H8BrNS
Molecular Weight	218.11 g/mol
Synonyms	3-(Methylthio)-2-bromopyridine; 2-Bromo-3-methylsulfanylpyridine; 2-Bromo-3-(methylmercapto)pyridine; Pyridine, 2-bromo-3-(methylthio)-; 2-Bromo-3-(methylsulfanyl)pyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-(Methylthio)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.