Description

2-Chloro-6-(trifluoromethyl)thiazolo[4,5-b]pyridine is a high-value, heterocyclic organic compound featuring a fused thiazole and pyridine ring system, distinguished by its chloro and trifluoromethyl substituents. This specific molecular architecture makes it a critical advanced pharmaceutical intermediate and a versatile building block in modern synthetic chemistry. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients. The compound is supplied with a CAS Number of 884860-62-2, ensuring precise identification and traceability for global regulatory and procurement processes.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for targeted therapies.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Used in the development of organic electronic materials, such as OLEDs and semiconductors, due to its electron-deficient heterocyclic core.
• Ligand and Catalyst Development: Employed in the design of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized as a core structure for creating fluorescent tags or bioactive probes in biochemical research.
• Custom Synthesis and Contract Manufacturing: A starting material for bespoke chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	2-Chloro-6-(trifluoromethyl)thiazolo[4,5-b]pyridine
CAS No.	884860-62-2
Molecular Formula	C7H2ClF3N2S
Molecular Weight	238.62 g/mol
Synonyms	2-Chloro-6-(trifluoromethyl)[1,3]thiazolo[4,5-b]pyridine; Thiazolo[4,5-b]pyridine, 2-chloro-6-(trifluoromethyl)-; 884860-62-2; 2-Chloro-6-trifluoromethylthiazolo[4,5-b]pyridine; 6-Trifluoromethyl-2-chlorothiazolo[4,5-b]pyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-6-(trifluoromethyl)thiazolo[4,5-b]pyridine is manufactured under a strict quality management system. We employ advanced analytical techniques including HPLC, GC-MS, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment. Our quality protocols are designed to meet the stringent requirements of pharmaceutical R&D and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC Area %)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.