Description

6-Fluoro-5-Iodopyridin-2-Amine is a high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents, makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of halogenated heterocycles.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers or organic light-emitting diodes (OLEDs).
• Chemical Biology Probe Synthesis: Utilized to create molecular probes for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A fundamental substrate for custom synthesis services catering to R&D and pilot-scale production needs.

Basic Information

Product Name	6-Fluoro-5-Iodopyridin-2-Amine
CAS No.	884660-47-3
Molecular Formula	C5H4FIN2
Molecular Weight	237.99 g/mol
Synonyms	2-Amino-6-fluoro-5-iodopyridine; 5-Iodo-6-fluoropyridin-2-amine; 6-Fluoro-5-iodo-2-pyridinamine; 2-Pyridinamine, 6-fluoro-5-iodo-; 884660-47-3; 6-Fluoro-5-iodopyridine-2-amine; 5-Iodo-6-fluoro-2-aminopyridine
EINECS	Contact for details

Quality Control

Our 6-Fluoro-5-Iodopyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.