Description

n-Methyl-4-[5-(Trifluoromethyl)pyridin-2-yl]benzylamine is a high-value, functionalized benzylamine derivative featuring a trifluoromethylpyridine moiety. This compound is a critical pharmaceutical intermediate and building block for advanced organic synthesis, prized for its ability to impart metabolic stability and modulate physicochemical properties in target molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or emissive materials for OLEDs.
• Chemical Biology Probes: Useful for constructing molecular probes and tags for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	n-Methyl-4-[5-(Trifluoromethyl)pyridin-2-yl]benzylamine
CAS No.	884507-35-1
Molecular Formula	C14H13F3N2
Molecular Weight	266.26 g/mol
Synonyms	1-[4-[[5-(Trifluoromethyl)-2-pyridinyl]phenyl]-N-methylmethanamine; 4-((5-(Trifluoromethyl)pyridin-2-yl)benzyl)(methyl)amine; N-Methyl-1-[4-[5-(trifluoromethyl)-2-pyridinyl]phenyl]methanamine; 2-[4-[(Methylamino)methyl]phenyl]-5-(trifluoromethyl)pyridine; 4-((Methylamino)methyl)-α,α,α-trifluoro-2-pyridinetoluene
EINECS	Contact for details

Quality Control

Our n-Methyl-4-[5-(Trifluoromethyl)pyridin-2-yl]benzylamine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment. Our quality commitment aligns with ISO 9001 standards, and we can support development projects requiring ICH stability guidelines or regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.