Description

2-Chloro-5-Picolinoylpyridine is a high-value pyridine derivative and a key chemical intermediate prized for its unique molecular architecture. This compound matters for its role as a sophisticated building block in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and other targeted therapeutic research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis for fine chemical manufacturing.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2-Chloro-5-Picolinoylpyridine
CAS No.	884504-81-8
Molecular Formula	C11H7ClN2O
Molecular Weight	218.64 g/mol
Synonyms	2-Chloro-5-(pyridine-2-carbonyl)pyridine; 5-(2-Chloropyridin-5-yl)-2-pyridinylmethanone; 2-Pyridinecarboxaldehyde, 5-(2-chloro-5-pyridinyl)-; (2-Chloropyridin-5-yl)(pyridin-2-yl)methanone; Picolinophenone, 2'-chloro-5'-derivative
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Picolinoylpyridine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.