Description

Methyl 3-Amino-5-Fluorobenzoate is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of active pharmaceutical ingredients (APIs) and sophisticated agrochemicals, where its unique fluorine and amino substituents enable precise molecular modifications. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex heterocyclic frameworks and fine-tuning biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced efficacy and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Dye & Pigment Manufacturing: Employed in the production of specialized fluorinated dyes and pigments for high-performance applications.
• Academic & Contract Research: A valuable reagent for methodological development and discovery chemistry in academic and contract research organizations (CROs).
• Custom Synthesis & Scale-up: Provides a reliable starting point for custom synthesis projects, from milligram-scale research to multi-kilogram pilot production.

Basic Information

Product Name	Methyl 3-Amino-5-Fluorobenzoate
CAS No.	884497-46-5
Molecular Formula	C8H8FNO2
Molecular Weight	169.15 g/mol
Synonyms	3-Amino-5-fluorobenzoic acid methyl ester; Methyl 3-amino-5-fluorobenzoate; 5-Fluoro-3-aminobenzoic Acid Methyl Ester; Benzoic acid, 3-amino-5-fluoro-, methyl ester; Methyl 5-fluoro-3-aminobenzoate; 3-Amino-5-fluorobenzoic Acid Methyl Ester; 5-Fluoro-m-aminobenzoic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our production of Methyl 3-Amino-5-Fluorobenzoate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We operate under a cGMP-compliant quality system suitable for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Unknown Impurity	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.