Description

3-Bromo-2-Fluoro-4-Picoline is a high-purity halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring bromine and fluorine substituents on the pyridine ring, makes it a versatile intermediate for introducing specific functional groups and modulating electronic properties in target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry for structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the halogenated pyridine core contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the creation of organic electronic materials, such as components for OLEDs or conductive polymers.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic and Industrial R&D: Utilized in exploratory chemistry for developing novel heterocyclic compounds and reaction methodologies.

Basic Information

Product Name	3-Bromo-2-Fluoro-4-Picoline
CAS No.	884495-46-9
Molecular Formula	C6H5BrFN
Molecular Weight	190.01 g/mol
Synonyms	2-Fluoro-3-bromo-4-methylpyridine; 4-Methyl-3-bromo-2-fluoropyridine; 3-Bromo-2-fluoro-4-methylpyridine; Pyridine, 3-bromo-2-fluoro-4-methyl-; 884495-46-9; 2-Fluoro-3-bromo-4-picoline
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Fluoro-4-Picoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality parameters. Our quality commitment supports applications requiring high-purity intermediates under GMP or ISO-guided conditions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.