Description

2-Chloro-3-Formyl-4-Picoline is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both chloro and formyl substituents on the pyridine ring, makes it a versatile precursor for constructing complex molecular architectures. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging its reactive sites for structural diversification.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of functionalized heterocyclic compounds for advanced materials, such as organic semiconductors or metal-organic frameworks (MOFs).
• Custom Synthesis and Contract Manufacturing: An essential building block for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Item	Detail
Product Name	2-Chloro-3-Formyl-4-Picoline
CAS No.	884495-45-8
Molecular Formula	C7H6ClNO
Molecular Weight	155.58 g/mol
Synonyms	2-Chloro-3-formyl-4-methylpyridine; 4-Methyl-2-chloropyridine-3-carboxaldehyde; 3-Formyl-2-chloro-4-picoline; 2-Chloro-4-methyl-3-pyridinecarboxaldehyde; 2-Chloro-3-pyridinecarboxaldehyde, 4-methyl-; 2-Chloro-4-methylnicotinaldehyde
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-3-Formyl-4-Picoline is manufactured under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee it meets the rigorous standards required for research and industrial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized, it is recommended to store the material under an inert atmosphere for long-term stability and to minimize degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.