Description

2-Bromo-3-Chloro-4-Picoline is a halogenated pyridine derivative of significant importance as a versatile synthetic intermediate in advanced organic chemistry. Its unique substitution pattern makes it a critical building block for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogenated motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the bromo and chloro substituents contribute to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials and liquid crystals.
• Custom Synthesis and Contract Manufacturing: A valuable scaffold for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	2-Bromo-3-Chloro-4-Picoline
CAS No.	884495-42-5
Molecular Formula	C6H5BrClN
Molecular Weight	206.47 g/mol
Synonyms	3-Chloro-2-bromo-4-methylpyridine; 4-Methyl-2-bromo-3-chloropyridine; 2-Bromo-3-chloro-4-methylpyridine; 2-Bromo-3-chloro-picoline; 3-Chloro-2-bromo-4-picoline
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Chloro-4-Picoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.