Description

5-Amino-2-Chloro-Nicotinic Acid Ethyl Ester is a high-purity, multi-functional chemical intermediate essential for advanced organic synthesis. Its molecular structure makes it a critical building block for creating complex heterocyclic compounds with significant commercial and research value. This product is primarily targeted at the pharmaceutical, agrochemical, and specialty chemical industries for the development of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its chloronicotinate scaffold.
• Organic Synthesis Building Block: Serves as a versatile reagent for constructing complex pyridine and fused-ring heterocyclic systems in research and development.
• Material Science Research: Employed in the creation of specialized ligands, functional polymers, and organic electronic materials.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in manufacturing processes.

Basic Information

Item	Details
Product Name	5-Amino-2-Chloro-Nicotinic Acid Ethyl Ester
CAS No.	884495-40-3
Molecular Formula	C8H9ClN2O2
Molecular Weight	200.62 g/mol
Synonyms	Ethyl 5-Amino-2-chloronicotinate; 2-Chloro-5-aminonicotinic Acid Ethyl Ester; 5-Amino-2-chloropyridine-3-carboxylic Acid Ethyl Ester; 3-Carbethoxy-5-amino-2-chloropyridine; 2-Chloro-5-aminopyridine-3-carboxylic Acid Ethyl Ester; Ethyl 2-Chloro-5-aminonicotinate; 5-Amino-2-chloro-3-pyridinecarboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our 5-Amino-2-Chloro-Nicotinic Acid Ethyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC chromatograms and NMR spectra, to verify identity and purity. Certificates of Analysis (COA) are available for every batch and supplied upon request, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.