Description

6-Chloro-3-Formyl-2-Picoline is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which incorporates both a reactive aldehyde group and a halogenated pyridine ring, enabling its use in the construction of complex pharmacophores and functional materials. This compound is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infectives.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a versatile starting material for creating complex chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes and inhibitors for biochemical and pharmacological research.
• Custom Synthesis and Contract Manufacturing: A critical raw material for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	6-Chloro-3-Formyl-2-Picoline
CAS No.	884495-36-7
Molecular Formula	C7H6ClNO
Molecular Weight	155.58 g/mol
Synonyms	2-Picoline, 6-chloro-3-formyl-; 6-Chloro-3-formyl-2-methylpyridine; 3-Formyl-6-chloro-2-picoline; 6-Chloro-2-methylpyridine-3-carboxaldehyde; 2-Methyl-6-chloropyridine-3-carbaldehyde; 6-Chloro-3-pyridinecarboxaldehyde, 2-methyl-; (6-Chloro-2-methylpyridin-3-yl)methanal
EINECS	Contact for details

Quality Control

Our 6-Chloro-3-Formyl-2-Picoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We are committed to meeting the stringent requirements of GMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.