Description

3-Amino-2-Bromo-5-Fluoropyridine is a high-purity, multi-functional halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring amino, bromo, and fluoro substituents, makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by R&D and production teams in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized nitrogen-containing ligands used in transition metal catalysis and material science.
• Functional Material Research: Employed in the synthesis of organic electronic materials, dyes, and photoactive compounds due to its electron-donating and -withdrawing substituents.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	3-Amino-2-Bromo-5-Fluoropyridine
CAS No.	884495-03-8
Molecular Formula	C5H4BrFN2
Molecular Weight	191.00 g/mol
Synonyms	2-Bromo-5-fluoro-3-pyridinamine; 5-Fluoro-2-bromo-3-aminopyridine; 2-Bromo-5-fluoropyridin-3-amine; 3-Amino-2-bromo-5-fluoropyridine; 884495-03-8; 3-Pyridinamine, 2-bromo-5-fluoro-; 2-Bromo-5-fluoro-3-aminopyridine
EINECS	Contact for details

Quality Control

Our 3-Amino-2-Bromo-5-Fluoropyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.