Description

4-Bromo-5-Fluoro-2-Hydroxy-3-Nitropyridine is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its unique halogenated and nitrated pyridine core makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its halogenated pyridine structure for bioactivity.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and material science.
• Functional Material Development: Employed in the research and production of advanced electronic materials and organic semiconductors.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Scale-Up: Supplied for contract research organizations (CROs) and CDMOs requiring reliable, high-quality building blocks for custom synthesis projects.

Basic Information

Item	Details
Product Name	4-Bromo-5-Fluoro-2-Hydroxy-3-Nitropyridine
CAS No.	884495-02-7
Molecular Formula	C5H2BrFN2O3
Molecular Weight	236.98 g/mol
Synonyms	3-Nitro-4-bromo-5-fluoro-2-pyridinol; 4-Bromo-5-fluoro-3-nitro-2(1H)-pyridinone; 2-Hydroxy-4-bromo-5-fluoro-3-nitropyridine; 4-Bromo-5-fluoro-2-hydroxy-3-nitro-pyridine; 4-Bromo-5-fluoro-3-nitropyridin-2-ol; 884495-02-7; AI3-63500
EINECS	Contact for details

Quality Control

Our 4-Bromo-5-Fluoro-2-Hydroxy-3-Nitropyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.