Description

2-Chloro-5-Fluoro-4-(Hydroxymethyl)Pyridine is a high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring chloro, fluoro, and hydroxymethyl substituents, makes it an essential intermediate for constructing complex pharmacologically active molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Chloro-5-Fluoro-4-(Hydroxymethyl)Pyridine
CAS No.	884494-86-4
Molecular Formula	C6H5ClFNO
Molecular Weight	161.56 g/mol
Synonyms	4-(Hydroxymethyl)-2-chloro-5-fluoropyridine; 2-Chloro-5-fluoro-4-pyridinemethanol; (2-Chloro-5-fluoro-4-pyridinyl)methanol; 5-Fluoro-2-chloro-4-(hydroxymethyl)pyridine; 2-Chloro-5-fluoro-4-(hydroxymethyl)pyridine; 884494-86-4; 2-Chloro-5-fluoro-4-pyridylmethanol
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Fluoro-4-(Hydroxymethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for research and commercial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.