Description

2-Fluoro-4-Iodonicotinic Acid Methyl Ester is a high-value, multi-functional heterocyclic building block used in advanced organic synthesis. This compound is critical for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogenated pyridine structure enables precise molecular modifications. It is primarily sought after by the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules in drug discovery and material science programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated and iodinated drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used to create novel pyridine-based herbicides, fungicides, and plant growth regulators with enhanced activity.
• Ligand & Catalyst Development: Serves as a versatile scaffold for constructing complex ligands used in transition metal catalysis and material science.
• Chemical Biology Probes: Employed in the development of molecular probes and tags for studying biological systems due to its halogen handles for further functionalization.
• Organic Electronics: A potential building block for synthesizing novel heterocyclic compounds used in organic light-emitting diodes (OLEDs) and semiconductors.

Basic Information

Product Name	2-Fluoro-4-Iodonicotinic Acid Methyl Ester
CAS No.	884494-84-2
Molecular Formula	C7H5FINO2
Molecular Weight	281.02 g/mol
Synonyms	Methyl 2-Fluoro-4-iodonicotinate; 4-Iodo-2-fluoropyridine-3-carboxylic Acid Methyl Ester; 3-Pyridinecarboxylic Acid, 2-Fluoro-4-iodo-, Methyl Ester; 2-Fluoro-4-iodo-3-pyridinecarboxylic Acid Methyl Ester; Methyl 2-Fluoro-4-iodo-3-pyridinecarboxylate; 884494-84-2; 2-Fluoro-4-iodonicotinic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Iodonicotinic Acid Methyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing all specifications is available with every shipment and upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.