Description

2-Chloro-5-Fluoro-6-Picoline is a high-purity, multi-functional heterocyclic building block of significant importance in modern synthetic chemistry. Its unique halogenated pyridine structure makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and chlorine substituents enhance biological activity.
• Material Science Research: Serves as a precursor for creating functionalized ligands, organic semiconductors, and liquid crystal materials.
• Chemical Biology & Proteomics: Employed as a versatile building block for synthesizing molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Chloro-5-Fluoro-6-Picoline
CAS No.	884494-78-4
Molecular Formula	C6H5ClFN
Molecular Weight	145.56 g/mol
Synonyms	2-Chloro-5-fluoro-6-methylpyridine; 6-Methyl-2-chloro-5-fluoropyridine; 5-Fluoro-2-chloro-6-picoline; 2-Chloro-5-fluoro-6-picoline; 5-Fluoro-2-chloro-6-methylpyridine; 2-Chloro-5-fluoro-6-methylpyridine; 6-Chloro-3-fluoro-2-methylpyridine (isomer reference)
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-5-Fluoro-6-Picoline is manufactured under a strict quality management system and undergoes comprehensive analytical testing. Our products are guaranteed to meet the high-purity standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.