Description

2-Chloro-5-Fluoroisonicotinic Acid is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogenated pyridine motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides with improved efficacy.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic processes and material science.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Fluorescent Dye and Sensor Chemistry: Acts as a building block for synthesizing fluorophores and molecular sensors.

Basic Information

Product Name	2-Chloro-5-Fluoroisonicotinic Acid
CAS No.	884494-74-0
Molecular Formula	C6H3ClFNO2
Molecular Weight	175.55 g/mol
Synonyms	2-Chloro-5-fluoropyridine-4-carboxylic acid; 5-Fluoro-2-chloroisonicotinic acid; 4-Pyridinecarboxylic acid, 2-chloro-5-fluoro-; 2-Chloro-5-fluoro-4-pyridinecarboxylic acid; 2-Chloro-5-fluoropyridine-4-carboxylic acid; 884494-74-0; 2-Chloro-5-fluoro-4-picolinic acid
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Fluoroisonicotinic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.