Description

3-Fluoro-5-Formyl-2-Methoxypyridine is a high-value pyridine derivative featuring both formyl and fluoro substituents, making it a versatile and reactive building block for advanced synthesis. This compound is critical for the development of novel active pharmaceutical ingredients (APIs) and functional materials, where its unique substitution pattern enables precise molecular modifications. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or photoactive compounds.
• Chemical Biology Probes: Utilized to create fluorescent tags or molecular probes for studying biological processes and enzyme activity.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	3-Fluoro-5-Formyl-2-Methoxypyridine
CAS No.	884494-73-9
Molecular Formula	C7H6FNO2
Molecular Weight	155.13 g/mol
Synonyms	2-Methoxy-3-fluoro-5-pyridinecarboxaldehyde; 5-Formyl-3-fluoro-2-methoxypyridine; 3-Fluoro-2-methoxy-5-pyridinecarboxaldehyde; 3-Fluoro-5-formyl-2-methoxypyridine; 884494-73-9; 2-Methoxy-3-fluoropyridine-5-carbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-5-Formyl-2-Methoxypyridine is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard pharmaceutical intermediate grade meets stringent internal specifications, with purity typically exceeding 97% (by HPLC). Certificates of Analysis (COA) detailing results for assay, related substances, residual solvents, and other critical parameters are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single impurity	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.