Description

Methyl 2-Bromo-6-Methylisonicotinate is a high-purity pyridine derivative and a versatile brominated building block for advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of complex molecules, particularly in pharmaceutical and agrochemical research. It is essential for chemists and manufacturers in life sciences and fine chemical industries seeking to introduce functionalized pyridine motifs into their target structures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require halogenated heterocyclic cores.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up production in fine chemical manufacturing.
• Academic & R&D Laboratories: Used in medicinal chemistry programs and methodological studies for C-C and C-N cross-coupling reactions.

Basic Information

Product Name	Methyl 2-Bromo-6-Methylisonicotinate
CAS No.	884494-71-7
Molecular Formula	C8H8BrNO2
Molecular Weight	230.06 g/mol
Synonyms	2-Bromo-6-methylisonicotinic acid methyl ester; Methyl 2-bromo-6-methylpyridine-4-carboxylate; 4-Pyridinecarboxylic acid, 2-bromo-6-methyl-, methyl ester; 2-Bromo-6-methyl-4-pyridinecarboxylic acid methyl ester; 2-Bromo-6-methylisonicotinate methyl ester; 2-Bromo-6-methyl-4-(methoxycarbonyl)pyridine
EINECS	Contact for details

Quality Control

Our Methyl 2-Bromo-6-Methylisonicotinate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of GMP and ISO standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.