Description

2-Chloro-3-Hydroxy-4-Picoline is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique substitution pattern, which allows for selective functionalization and incorporation into complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal catalysis and organocatalysts due to the chelating potential of the pyridine nitrogen and hydroxyl group.
• Material Science Research: Acts as a monomer or functionalizing agent in the creation of advanced polymers and organic electronic materials.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	2-Chloro-3-Hydroxy-4-Picoline
CAS No.	884494-70-6
Molecular Formula	C6H6ClNO
Molecular Weight	143.57 g/mol
Synonyms	3-Hydroxy-2-chloro-4-methylpyridine; 2-Chloro-3-hydroxy-4-methylpyridine; 4-Methyl-2-chloro-3-pyridinol; 3-Pyridinol, 2-chloro-4-methyl-; 2-Chloro-4-methylpyridin-3-ol; 4-Picoline, 2-chloro-3-hydroxy-
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Hydroxy-4-Picoline is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.