Description

2-Chloro-5-Fluoro-4-Iodopyridine is a high-purity halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its unique substitution pattern, which provides multiple reactive sites for selective functionalization, enabling the construction of complex molecular architectures. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents, including herbicides and fungicides.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in cross-coupling and other metal-mediated reactions.
• Material Science Research: Employed in the synthesis of functionalized organic materials and liquid crystals.
• Chemical Biology Probes: Useful for synthesizing tagged molecules and probes for biochemical and diagnostic applications.
• Custom Synthesis Building Block: Provides a versatile scaffold for contract research organizations (CROs) and custom synthesis houses to fulfill client-specific molecular targets.

Basic Information

Product Name	2-Chloro-5-Fluoro-4-Iodopyridine
CAS No.	884494-49-9
Molecular Formula	C5H2ClFIN
Molecular Weight	273.43 g/mol
Synonyms	4-Iodo-2-chloro-5-fluoropyridine; 2-Chloro-5-fluoro-4-iodopyridine; 5-Fluoro-2-chloro-4-iodopyridine; Pyridine, 2-chloro-5-fluoro-4-iodo-; 884494-49-9; 2-Chloro-5-fluoro-4-iodo-pyridine; 4-Iodo-2-chloro-5-fluoro-pyridine
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Fluoro-4-Iodopyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment ensures the material meets the high standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.