Description

2-Fluoro-3-Iodo-6-Methylpyridine is a high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents, makes it an exceptionally versatile intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel agrochemicals, pharmaceuticals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of halogenated heterocycles.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or photoactive compounds.
• Cross-Coupling Reactions: The iodine moiety makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Sonogashira) to form biaryl systems.
• Fluorinated Compound Libraries: Integral for building diverse screening libraries in medicinal chemistry, exploring the effects of fluorine substitution.

Basic Information

Item	Details
Product Name	2-Fluoro-3-Iodo-6-Methylpyridine
CAS No.	884494-48-8
Molecular Formula	C6H5FIN
Molecular Weight	237.01 g/mol
Synonyms	6-Methyl-2-fluoro-3-iodopyridine; 3-Iodo-2-fluoro-6-picoline; 2-Fluoro-3-iodo-6-picoline; 2-Fluoro-3-iodo-6-methylpyridine; 884494-48-8; 3-Iodo-2-fluoro-6-methylpyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-3-Iodo-6-Methylpyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.