Description

2-Fluoro-4-Iodo-6-Picoline is a halogenated pyridine derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and valuable building block for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. Its unique substitution pattern makes it a critical intermediate for researchers and manufacturers in medicinal chemistry, material science, and fine chemical production.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of fluorinated and iodinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of novel pesticides, herbicides, and fungicides that require halogenated heterocyclic cores.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and advanced polymers.
• Chemical Biology Probes: Useful for creating molecular probes and tags for imaging and diagnostic applications due to the iodine atom.
• Custom Synthesis and R&D: A critical starting material for contract research organizations (CROs) and fine chemical companies engaged in custom synthesis projects.

Basic Information

Product Name	2-Fluoro-4-Iodo-6-Picoline
CAS No.	884494-45-5
Molecular Formula	C6H5FIN
Molecular Weight	237.01 g/mol
Synonyms	2-Fluoro-4-iodo-6-methylpyridine; 4-Iodo-2-fluoro-6-picoline; 6-Methyl-4-iodo-2-fluoropyridine; 2-Fluoro-4-iodo-6-methylpyridine; 2-Fluoro-4-iodo-6-picoline; 4-Iodo-2-fluoro-6-methylpyridine; 2-Fluoro-4-iodo-6-picoline (CAS 884494-45-5)
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Iodo-6-Picoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.