Description

2-Chloro-4-Iodopyridine-3-Methanol is a high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an indispensable intermediate for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. This compound is primarily sought by research chemists and process development scientists in fine chemical and active pharmaceutical ingredient (API) manufacturing for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Building block for synthesizing functionalized polymers or organic electronic materials with specific optoelectronic properties.
• Cross-Coupling Reactions: The iodine and chlorine substituents make it an excellent substrate for sequential palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Chemical Biology Probes: Used to develop molecular probes for studying biological processes and enzyme functions.

Basic Information

Product Name	2-Chloro-4-Iodopyridine-3-Methanol
CAS No.	884494-44-4
Molecular Formula	C6H5ClINO
Molecular Weight	269.47 g/mol
Synonyms	3-(Hydroxymethyl)-2-chloro-4-iodopyridine; (2-Chloro-4-iodopyridin-3-yl)methanol; 2-Chloro-4-iodo-3-pyridinemethanol; 2-Chloro-4-iodopyridin-3-ylmethanol; 884494-44-4; 3-Pyridinemethanol, 2-chloro-4-iodo-
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4-Iodopyridine-3-Methanol is manufactured under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.