Description

3-Bromo-2-Chloro-5-Fluoropyridine is a high-purity halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique substitution pattern, which allows for selective functionalization and the construction of complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its halogen handles for further coupling reactions.
• Material Science Precursor: Employed in the creation of functionalized ligands for catalysts and as a monomer or building block for specialty polymers and electronic materials.
• Cross-Coupling Reactions: Serves as an excellent substrate for various metal-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) due to the presence of the bromo substituent.
• Chemical Research & Development: Utilized in academic and industrial R&D labs for methodological studies and the exploration of new synthetic pathways in heterocyclic chemistry.

Basic Information

Product Name	3-Bromo-2-Chloro-5-Fluoropyridine
CAS No.	884494-36-4
Molecular Formula	C5H2BrClFN
Molecular Weight	210.43 g/mol
Synonyms	2-Chloro-3-bromo-5-fluoropyridine; 5-Fluoro-3-bromo-2-chloropyridine; 3-Bromo-2-chloro-5-fluoro-pyridine; Pyridine, 3-bromo-2-chloro-5-fluoro-; 884494-36-4 (CAS); 2-Chloro-3-bromo-5-fluoro-pyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Chloro-5-Fluoropyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.