Description

Benzyl 7'-Chloro-2'-Oxo-1',2'-Dihydrospiro[Piperidine-4,4'-Pyrido[2,3-D][1,3]Oxazine]-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex spirocyclic and fused heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders. It is primarily required by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of next-generation therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug candidates, especially in medicinal chemistry research and development.
• API Synthesis: Used as a core scaffold for constructing novel Active Pharmaceutical Ingredients (APIs) with potential neurological or psychiatric applications.
• Medicinal Chemistry Research: A valuable compound for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Development & Scale-Up: Employed in developing and optimizing robust, scalable synthetic routes for potential commercial manufacturing.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development, quality control, and regulatory submissions.
• Custom Synthesis: Acts as a starting material for the custom synthesis of derivatives and analogs for specialized research projects.

Basic Information

Item	Detail
Product Name	Benzyl 7'-Chloro-2'-Oxo-1',2'-Dihydrospiro[Piperidine-4,4'-Pyrido[2,3-D][1,3]Oxazine]-1-Carboxylate
CAS No.	883984-95-0
Molecular Formula	C19H18ClN3O3
Molecular Weight	371.82 g/mol
Synonyms	Benzyl 7'-chloro-2'-oxo-1',2'-dihydrospiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazine]-1-carboxylate; 1-[(Benzyloxy)carbonyl]-7'-chloro-1',2'-dihydro-2'-oxospiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazine]; Spiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazine]-1-carboxylic acid, 7'-chloro-1',2'-dihydro-2'-oxo-, benzyl ester; Benzyl 7-chloro-2-oxo-1,2-dihydrospiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazine]-1-carboxylate
EINECS	Contact for details

Quality Control

Every batch of Benzyl 7'-Chloro-2'-Oxo-1',2'-Dihydrospiro[Piperidine-4,4'-Pyrido[2,3-D][1,3]Oxazine]-1-Carboxylate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency that meet the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider conditions under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.