Description

4-(Pyridin-3-Ylsulfanyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a piperidine core with a pyridinylsulfanyl substituent. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for constructing complex molecules with potential biological activity. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel drug candidates, particularly in areas targeting the central nervous system and other therapeutic fields.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes for clinical trial material and commercial production.
• Ligand and Catalyst Synthesis: Employed in the preparation of specialized ligands for catalysis or as a precursor for functionalized materials.
• Chemical Biology Probes: Utilized to create tool compounds for studying biological pathways and target validation.

Basic Information

Product Name	4-(Pyridin-3-Ylsulfanyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	883555-05-3
Molecular Formula	C15H22N2O2S
Molecular Weight	294.41 g/mol
Synonyms	tert-Butyl 4-(pyridin-3-ylsulfanyl)piperidine-1-carboxylate; 1-Boc-4-(3-pyridylthio)piperidine; 4-(3-Pyridylthio)piperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(3-pyridylthio)piperidine; 4-(Pyridin-3-ylthio)piperidine-1-carboxylic acid tert-butyl ester; 4-(3-Pyridinylthio)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; N-Boc-4-(3-pyridylthio)piperidine
EINECS	Contact for details

Quality Control

Our 4-(Pyridin-3-Ylsulfanyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.