Description

m-Peg4-T-Butyl Ester is a high-purity, functionalized polyethylene glycol (PEG) derivative featuring a terminal tert-butyl ester group. This compound is a critical intermediate and building block in the synthesis of complex molecules, offering a protected carboxylic acid functionality for advanced conjugation chemistry. It is primarily utilized by researchers and manufacturers in the pharmaceutical, bioconjugation, and advanced materials sectors for developing prodrugs, linkers, and modified biomolecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and prodrugs requiring a protected carboxylic acid group.
• Bioconjugation & Linker Chemistry: Used to create PEGylated linkers for attaching drugs, dyes, or other functional groups to proteins, antibodies, or nanoparticles.
• Polymer & Materials Science: Serves as a monomer or modifying agent for creating functionalized polymers with tailored solubility and biocompatibility.
• Protecting Group Strategy: The tert-butyl ester acts as a robust protecting group for carboxylic acids during multi-step organic syntheses.
• Research & Development: Essential tool compound in medicinal chemistry and chemical biology for exploring new drug delivery systems and molecular constructs.

Basic Information

Product Name	m-Peg4-T-Butyl Ester
CAS No.	883554-11-8
Molecular Formula	C17H34O7
Molecular Weight	350.45 g/mol
Synonyms	1-(tert-Butoxy)-3,6,9,12-tetraoxapentadecan-15-oic Acid; tert-Butyl 3,6,9,12-tetraoxapentadecan-15-oate; mPEG4-t-butyl ester; 4,7,10,13-Tetraoxahexadecanoic Acid, 16-tert-Butyl Ester; PEG4 tert-Butyl Ester; Amino-PEG4-t-butyl ester (common precursor name); α-Methyl-ω-(tert-butoxycarbonyl) tetraethylene glycol
EINECS	Contact for details

Quality Control

Our m-Peg4-T-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance in GMP-related applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.