Description

1-n-Boc-4-(3-Aminomethylpyridyl)Piperidine is a high-purity, protected piperidine derivative of significant importance in modern pharmaceutical research and development. This compound serves as a critical advanced pharmaceutical intermediate (API intermediate), enabling the synthesis of complex molecules with targeted biological activity. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors for constructing novel drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its versatile piperidine-pyridine scaffold.
• Peptidomimetic Synthesis: Employed in the design and construction of peptidomimetics and other bioactive compounds that mimic natural peptides.
• Library Synthesis for Drug Discovery: A valuable reagent for generating diverse compound libraries in high-throughput screening (HTS) programs.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Ligand and Catalyst Preparation: Can be utilized to create specialized ligands for catalysis or as a component in organocatalysts.

Basic Information

Product Name	1-n-Boc-4-(3-Aminomethylpyridyl)Piperidine
CAS No.	883516-43-6
Molecular Formula	C16H25N3O2
Molecular Weight	291.39 g/mol
Synonyms	1-Boc-4-(3-(aminomethyl)pyridin-2-yl)piperidine; tert-Butyl 4-[3-(aminomethyl)pyridin-2-yl]piperidine-1-carboxylate; 2-(1-Boc-4-piperidyl)-3-(aminomethyl)pyridine; 4-(3-Aminomethylpyridin-2-yl)piperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(3-(aminomethyl)pyridin-2-yl)piperidine; N-Boc-4-(3-aminomethyl-2-pyridyl)piperidine; 883516-43-6
EINECS	Contact for details

Quality Control

Our 1-n-Boc-4-(3-Aminomethylpyridyl)Piperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.