Description

6-Chloro-2-Fluoro-3-Hydroxypyridine is a high-value halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogen and hydroxyl functionalities into heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects requiring specific halogen substitution patterns.

Basic Information

Product Name	6-Chloro-2-Fluoro-3-Hydroxypyridine
CAS No.	883107-68-4
Molecular Formula	C5H3ClFNO
Molecular Weight	147.53 g/mol
Synonyms	3-Hydroxy-6-chloro-2-fluoropyridine; 2-Fluoro-6-chloro-3-hydroxypyridine; 6-Chloro-2-fluoro-3-pyridinol; 2-Fluoro-6-chloro-3-pyridinol; 883107-68-4; 3-Pyridinol, 6-chloro-2-fluoro-; 6-Chloro-2-fluoropyridin-3-ol
EINECS	Contact for details

Quality Control

Our 6-Chloro-2-Fluoro-3-Hydroxypyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with complete batch data are provided to guarantee traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.