Description

5-Bromopyridine-3-β-Oxo-Propanoic Acid Ethyl Ester is a high-purity brominated pyridine derivative that serves as a versatile and critical building block in advanced organic synthesis. Its molecular structure, featuring both a bromine substituent and an active ester moiety, makes it an invaluable intermediate for constructing complex heterocyclic systems and functionalized molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Building block for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Versatile reagent for cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic substitution reactions due to the reactive bromine atom.
• Academic & R&D: Essential for methodological studies and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	5-Bromopyridine-3-β-Oxo-Propanoic Acid Ethyl Ester
CAS No.	883107-60-6
Molecular Formula	C10H10BrNO3
Molecular Weight	272.10 g/mol
Synonyms	Ethyl 3-(5-bromopyridin-3-yl)-3-oxopropanoate; 3-Oxo-3-(5-bromopyridin-3-yl)propanoic acid ethyl ester; 5-Bromo-3-pyridinyl 3-oxopropanoate ethyl ester; 5-Bromonicotinoylacetic acid ethyl ester; Ethyl (5-bromonicotinoyl)acetate; 883107-60-6; 5-Bromopyridine-3-β-oxo-propanoic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 5-Bromopyridine-3-β-Oxo-Propanoic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to cGMP principles and adherence to ISO standards guarantee a reliable supply of high-grade material for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination. Handle and store in accordance with all applicable local and international regulations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.