Description

2-Butenoic Acid, 4-Oxo-4-[4-[4-(Trifluoromethyl)-2-Pyridinyl]-1-Piperazinyl]- is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial importance due to its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the trifluoromethylpyridine moiety for enhanced biological activity.
• Chemical Synthesis: Serves as a versatile building block for creating complex piperazine and pyridine derivatives in medicinal chemistry.
• Life Science Research: Employed in biochemical and pharmacological studies as a reference standard or a tool compound for target validation.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	2-Butenoic Acid, 4-Oxo-4-[4-[4-(Trifluoromethyl)-2-Pyridinyl]-1-Piperazinyl]-
CAS No.	883030-85-1
Molecular Formula	C14H14F3N3O2
Molecular Weight	313.28 g/mol
Synonyms	4-[4-[4-(Trifluoromethyl)pyridin-2-yl]piperazin-1-yl]-4-oxobut-2-enoic acid; 4-Oxo-4-(4-(4-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)but-2-enoic acid; 2-Butenoic acid, 4-oxo-4-[4-[4-(trifluoromethyl)-2-pyridinyl]-1-piperazinyl]-; TFMPP Butenoic Acid Derivative; (E)-4-[4-[4-(Trifluoromethyl)-2-pyridinyl]-1-piperazinyl]-4-oxo-2-butenoic acid
EINECS	Contact for details

Quality Control

Our 2-Butenoic Acid, 4-Oxo-4-[4-[4-(Trifluoromethyl)-2-Pyridinyl]-1-Piperazinyl]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects with material suitable for research use and can supply grades aligned with cGMP guidelines for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in the original packaging to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.