Description

3H-1,2,4-Triazol-3-One, 2,4-Dihydro-4-[2-(Trifluoromethyl)Phenyl]-5-[[4-(Trifluoromethyl)-2-Pyridinyl]Thio]- is a sophisticated heterocyclic compound featuring a triazolone core flanked by trifluoromethylphenyl and pyridinylthio substituents, making it a valuable advanced pharmaceutical intermediate and key building block for medicinal chemistry research. Its molecular architecture is specifically engineered to impart unique physicochemical properties, crucial for modulating biological activity and pharmacokinetic profiles in drug discovery. This high-purity compound is primarily targeted at pharmaceutical R&D and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly in therapeutic areas targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used as a key scaffold for developing new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl groups.
• Medicinal Chemistry Building Block: Employed in structure-activity relationship (SAR) studies and combinatorial chemistry libraries to explore new chemical entities.
• Chemical Biology Probe: Utilized in biochemical assays to study enzyme inhibition or receptor-ligand interactions due to its specific heterocyclic structure.
• Material Science Research: Investigated as a potential monomer or additive for creating specialty polymers with unique thermal or optical properties.

Basic Information

Product Name	3H-1,2,4-Triazol-3-One, 2,4-Dihydro-4-[2-(Trifluoromethyl)Phenyl]-5-[[4-(Trifluoromethyl)-2-Pyridinyl]Thio]-
CAS No.	883028-74-8
Molecular Formula	C15H8F6N4OS
Molecular Weight	406.31 g/mol
Synonyms	4-[2-(Trifluoromethyl)phenyl]-5-{[4-(trifluoromethyl)pyridin-2-yl]sulfanyl}-2,4-dihydro-3H-1,2,4-triazol-3-one; 2,4-Dihydro-4-[2-(trifluoromethyl)phenyl]-5-[[4-(trifluoromethyl)-2-pyridinyl]thio]-3H-1,2,4-triazol-3-one; CAS 883028-74-8; 1,2,4-Triazol-3(2H)-one, 4-[2-(trifluoromethyl)phenyl]-5-[[4-(trifluoromethyl)-2-pyridinyl]thio]-2,4-dihydro-
EINECS	Contact for details

Quality Control

Our production of 3H-1,2,4-Triazol-3-One, 2,4-Dihydro-4-[2-(Trifluoromethyl)Phenyl]-5-[[4-(Trifluoromethyl)-2-Pyridinyl]Thio]- adheres to stringent GMP and ISO 9001 guidelines, ensuring batch-to-batch consistency and traceability. Each lot undergoes comprehensive analytical characterization using HPLC, NMR, and MS to confirm identity and purity. A detailed Certificate of Analysis (COA) documenting purity, related substances, and residual solvents is provided with every shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.