Description

4-[3-(Methylsulfonyl)Phenyl]-1-Propylpiperidine, Hydrochloride is a high-purity, synthetically derived organic compound of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block or intermediate in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new therapeutic agents. The hydrochloride salt form enhances stability and handling properties for precise formulation work.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, especially for neurological and psychiatric applications.
• Chemical Reference Standard: Used as a high-purity standard in analytical method development, validation, and quality control within pharmaceutical laboratories.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Process Chemistry Development: Serves as a critical intermediate during scale-up and optimization of API synthesis routes for clinical and commercial manufacturing.
• Academic & Institutional Research: Utilized in universities and research institutes for pharmacological studies and the exploration of new therapeutic mechanisms.

Basic Information

Product Name	4-[3-(Methylsulfonyl)Phenyl]-1-Propylpiperidine, Hydrochloride
CAS No.	882737-42-0
Molecular Formula	C15H23NO2S • HCl
Molecular Weight	317.87 g/mol (as hydrochloride salt)
Synonyms	1-Propyl-4-[3-(methylsulfonyl)phenyl]piperidine hydrochloride; 4-(3-Methanesulfonylphenyl)-1-propylpiperidine HCl; 882737-42-0; 4-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine HCl; 1-Propyl-4-(3-methylsulfonylphenyl)piperidine hydrochloride; 4-(3-Methylsulfonylphenyl)-1-propylpiperidine hydrochloride; Piperidine, 4-[3-(methylsulfonyl)phenyl]-1-propyl-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 4-[3-(Methylsulfonyl)Phenyl]-1-Propylpiperidine, Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development purposes. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via techniques such as HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.