Description

4-Methyl-2-(Phenylmethoxy)-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-Pyridine is a high-value, multi-functional boronic ester derivative, serving as a critical synthetic intermediate in modern organic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in creating complex heterocyclic cores prevalent in drug discovery.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific biaryl motifs.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as ligands for catalysts or components for organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Serves as a precursor for creating tagged molecules or probes used in biochemical and medicinal chemistry research.
• Cross-Coupling Reactions: Primarily utilized in palladium-catalyzed Suzuki-Miyaura cross-coupling to form carbon-carbon bonds between aromatic rings.
• Library Synthesis: A valuable reagent for the parallel and combinatorial synthesis of diverse compound libraries for high-throughput screening.

Basic Information

Product Name	4-Methyl-2-(Phenylmethoxy)-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-Pyridine
CAS No.	882679-44-9
Molecular Formula	C23H30BNO3
Molecular Weight	379.30 g/mol
Synonyms	2-(Benzyloxy)-4-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(phenylmethoxy)-4-methylpyridine; 4-Methyl-2-(benzyloxy)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; Pinacol 2-(Benzyloxy)-4-methylpyridine-3-boronate; 2-(Benzyloxy)-4-methylpyridine-3-boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 4-Methyl-2-(Phenylmethoxy)-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-Pyridine is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.