Description

4-Bromo-2-(4H-1,2,4-Triazol-3-Yl)Aniline is a high-purity, advanced pharmaceutical intermediate characterized by its unique molecular structure combining an aniline derivative with a 1,2,4-triazole moiety. This compound is of critical importance for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new drugs, agrochemicals, and other specialized fine chemicals where precise bromo- and triazole-substituted aniline chemistry is required.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and pesticides that leverage the bioactivity of the triazole ring system.
• Material Science: Acts as a monomer or functionalizing agent in the creation of advanced polymers and ligands for catalytic systems.
• Chemical Synthesis: Employed in organic synthesis for the construction of complex heterocyclic compounds and as a reagent in cross-coupling reactions.
• Bioconjugation & Probe Development: Utilized in the design of biochemical probes and diagnostic agents due to its reactive amine and halogen functional groups.

Basic Information

Product Name	4-Bromo-2-(4H-1,2,4-Triazol-3-Yl)Aniline
CAS No.	882517-93-3
Molecular Formula	C8H7BrN4
Molecular Weight	239.07 g/mol
Synonyms	3-(2-Amino-5-bromophenyl)-4H-1,2,4-triazole; 2-Amino-5-bromo-1,2,4-triazol-1-ylbenzene; 4-Bromo-2-(1H-1,2,4-triazol-3-yl)aniline; 5-Bromo-2-(4H-1,2,4-triazol-3-yl)benzenamine; 882517-93-3; Aniline, 4-bromo-2-(4H-1,2,4-triazol-3-yl)-; 4-Bromo-2-(1,2,4-triazol-3-yl)aniline
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-(4H-1,2,4-Triazol-3-Yl)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and hygroscopic; therefore, containers should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.