Description

5-Bromo-6-Trifluoromethyl-Pyridin-2-Ylamine is a high-value, multi-functional pyridine derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both bromo and trifluoromethyl substituents, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for functionalized ligands and organic electronic materials in the development of OLEDs and other specialty polymers.
• Chemical Biology & Proteomics: Employed as a versatile scaffold for creating molecular probes and tool compounds used in target identification and validation studies.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis organizations (CSOs) and CDMOs serving the life sciences sector.

Basic Information

Product Name	5-Bromo-6-Trifluoromethyl-Pyridin-2-Ylamine
CAS No.	882500-21-2
Molecular Formula	C7H4BrF3N2
Molecular Weight	241.02 g/mol
Synonyms	2-Amino-5-bromo-6-(trifluoromethyl)pyridine; 5-Bromo-6-(trifluoromethyl)pyridin-2-amine; 5-Bromo-6-trifluoromethyl-2-pyridinamine; 2-Pyridinamine, 5-bromo-6-(trifluoromethyl)-; 882500-21-2; 5-Bromo-6-trifluoromethyl-2-aminopyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-6-Trifluoromethyl-Pyridin-2-Ylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.