Description

1H-Indazole-1-Carboxylic Acid, 3-Formyl-, 1,1-Dimethylethyl Ester is a high-purity, functionalized indazole derivative serving as a critical advanced pharmaceutical intermediate (API). Its molecular structure, featuring both formyl and tert-butyl ester protecting groups, makes it a versatile key building block for synthesizing complex bioactive molecules. This compound is primarily required by R&D and production teams in the pharmaceutical and agrochemical industries for developing new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used as a building block for developing new generation pesticides and herbicides with specific modes of action.
• Chemical Biology Research: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme function and signal transduction pathways.
• Material Science: Potential monomer or precursor for creating specialized polymers and organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Sourced by CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring high-purity intermediates.

Basic Information

Item	Detail
Product Name	1H-Indazole-1-Carboxylic Acid, 3-Formyl-, 1,1-Dimethylethyl Ester
CAS No.	882188-88-7
Molecular Formula	C13H14N2O3
Molecular Weight	246.26 g/mol
Synonyms	tert-Butyl 3-formyl-1H-indazole-1-carboxylate; 3-Formyl-1H-indazole-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-3-formyl-1H-indazole; 1-Boc-3-formylindazole; Boc-3-formylindazole; 3-Formylindazole-1-carboxylic acid tert-butyl ester; 1H-Indazole-1-carboxylic acid, 3-formyl-, 1,1-dimethylethyl ester; tert-Butyl 3-formylindazole-1-carboxylate
EINECS	Contact for details

Quality Control

Our production of 1H-Indazole-1-Carboxylic Acid, 3-Formyl-, 1,1-Dimethylethyl Ester adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided with each shipment. We support cGMP compliance for pharmaceutical applications, and our quality protocols are designed to meet the exacting standards of global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be sensitive to moisture and prolonged exposure to air; for long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.